siRNA Synthesis (Guaranteed)

siRNA Synthesis (Guaranteed)

Algorithm-optimized triplex design
Consistent lot-to-lot performance
Low off-target effects

Service Features

siRNA consists of 21-25 nt double-stranded RNA, HPLC-purified for direct cell transfection. Our guaranteed service ensures ≥70% silencing efficiency.

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Service Overview

siRNA is a designed short double-stranded RNA and a core tool of RNA interference that specifically degrades target mRNA to silence genes. Our standard siRNA is 21-25 nt double-stranded RNA, HPLC-purified for direct cell transfection, supplied as lyophilized powder with dosage stated in moles, and backed by a three-for-one guarantee.

Service Advantages

  • Proprietary siRNA design technology with at least 70% silencing efficiency and guaranteed cell transfection efficiency (at least 80%).
  • After-sales service: if qRT-PCR shows that none of the three siRNAs in the package reaches 70% silencing and the issue is confirmed as design-related, we will redesign and synthesize three new siRNAs targeting the gene free of charge (excluding species other than human, rat, and mouse, as well as lncRNA).

Service Workflow

Order intake|Synthesis|Purification|QC|Packaging|Final inspection|Shipping

Customer Provides

Provide the exact 19 nt target sequence and overhangs for siRNA synthesis, or the gene name, sequence, and specifications to be designed. The three-for-one package must be designed by Proabbio; customer-supplied sequences are not covered by the guarantee.

Service Description

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ItemDescription
DeliverablesThree pairs of target gene siRNAs (3x2 OD each), three pairs of controls (1x1 OD each), and one tube of DEPC water (1 mL), 10 tubes total.
Order gene information file.
Test report.
siRNA user manual.
NotesSpecific scope, sample requirements, and acceptance criteria are subject to the project plan confirmed by both parties.

Ready to Start Your Project?

Our technical team can help with experimental design, sample evaluation and study execution. Contact us for a consultation or quote.

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